LIVE MARKET·450 SC postings · last 180 days·Updated April 30, 2026

Registered Nurse (RN) salary in South Carolina: $50.25/hr$2,010/wk$104,520/yr median.

Pay range $40.00$1,600$83,200–$66.50/hr$2,660/wk$138,320/yr across the middle 50% of 450 active South Carolina postings from 115 employers.

5.8% above the national Registered Nurse (RN) median of $47.50/hr · #28 of 51 states with live data.

Show pay as
Median /hr/wk/yr
$50.25$2,010$104,520
P25–P75
$40.00$1,600$83,200–$66.50$2,660$138,320
middle 50%
Postings
450
last 180 days
Employers
115
in SC
01·NEIGHBORING STATES·REGISTERED NURSE (RN)

How South Carolina compares with its neighbors.

04·FREQUENTLY ASKED·REGISTERED NURSE (RN) · SC

Registered Nurse (RN) pay in South Carolina, answered.

How much does a Registered Nurse (RN) make in South Carolina?

The median Registered Nurse (RN) pay in South Carolina is $50.25/hr (about $104,520/yr), based on 450 job postings with listed pay over the last 180 days.

What is the Registered Nurse (RN) pay range in South Carolina?

The middle 50% of South Carolina postings pay $40.00–$66.50/hr. Listed pay runs from $5.50 to $85.75/hr.

Do Registered Nurse (RN)s in South Carolina earn more than the national average?

South Carolina pays 5.8% more than the national Registered Nurse (RN) median of $47.50/hr, ranking #28 of 51 states with live data.

How many employers are hiring Registered Nurse (RN)s in South Carolina?

115 employers posted Registered Nurse (RN) roles with listed pay in South Carolina over the last 180 days.

Figures come from active US healthcare job postings with listed pay in South Carolina, collected over the last 180 days. States with fewer than 50 postings are shown on the national page only.